Progresses of the pathogenesis of rotavirus infection / 国际儿科学杂志

ABSTRACT

Rotavirus is the most important pathogen causing severe diarrhea in infants and young children worldwide,and for rotavirus diarrhea there is no specific treatment so far.At present,there are a variety of claims on the pathogenesis of rotavirus infection,but none is conclusive.In the process of infection,rotavirus pathogens must overcome antiviral innate immune response that can replicate in host cell.Rotavirus encoded proteins play an important role in the process of rotavirus infection.This paperreviews the role of rotavirus encoding proteins in the pathogenesis of rotavirus infection.