Application of Polysorbate 80 in Microbial Limit Test / 中国药师
China Pharmacist
;
(12): 1776-1777, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-475720
ABSTRACT
Objective:
To provide appropriate test liquid preparation methods for antibacterial or water-insoluble drugs, and estab-lish a convenient and effective method for microbial limit test.Methods:
Using function of polysorbate 80 as neutralization, emulsifica-tion, solubilization and microbial protection, We carried out the liquid preparations were prepared and microbial limit test validation was carried out for 11 kinds of hospital drugs.Results:
The bacteria recovery rate and the control bacteria test were in accordance with the requirement of pharmacopoeia.Conclusion:
Polysorbate 80 can be used in the microbial limit test of the drugs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
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