Optimization of β-Cyclodextrin Inclusion Process for Volatile Oil in Yingxinning Capsules by Orthogonal Test / 中国药师
China Pharmacist
;
(12): 1680-1681, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-475745
ABSTRACT
Objective:
To optimize β-cyclodextrin (β-CD) inclusion process for volatile oil in Yingxinning capsules.Methods:
The content of volatile oil in theβ-CD inclusion compound as the evaluation index, the ratio of volatile oil toβ-CD, inclusion tempera-ture, inclusion time and stirring speed as the influencing factors, the inclusion process was studied using L9(34)orthogonal design. Re-sultsThe best preparation conditions were as followsthe ratio of volatile oil toβ-CD was 1∶ 9, the inclusion temperature was 40℃, the inclusion time was 30min and the stirring speed was 800 r·min-1 .Conclusion:
The preparation technology is simple, feasible and stable with high inclusion rate of volatile oil.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
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