Enteral nutrition with omega-3 polyunsaturated fatty acid in acute respiratory distress syndrome / 中国小儿急救医学
Chinese Pediatric Emergency Medicine
;
(12): 760-763, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-475768
ABSTRACT
Acute respiratory distress syndrome (ARDS) is a common clinical critical disease threatening patient's life,inflammation caused by diffuse alveolar damage is the essence.Omega-3 polyunsaturated fatty acid(ω-3PUFAs) can inhibit inflammation by decreasing arachidonic acid metabolites through competing with arachidonic acid by a variety of ways,by changing the nature of cell membrane signal platform lipid rafts,by involving in inflammation regression and tissue repairment using its metabolites,by reducing the activation of nulear factors-κB and inhibiting the release of inflammatory mediators in local lung tissue.So,ω-3PUFAs has become the research hot spot in ARDS drug treatment.The clinical study on ω-3PUFAs enteral nutrition in the treatment of ARDS has not yet reached the consistent conclusion,therefore,the multicenter randomized controlled trial is needed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Chinese Pediatric Emergency Medicine
Year:
2014
Type:
Article
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