Anti-inflammatory and Analgesic Effects of Different Extracts of Folium Pyrrosiae / 中国药师
China Pharmacist
;
(12): 1642-1644, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-475785
ABSTRACT
Objective:
To study the anti-inflammatory and analgesic effects of different solvent extracts of Folium Pyrrosiae. Meth-odsWater extract and 75% alcohol extract of Folium Pyrrosiae were obtained. Mouse auricle swelling model induced by xylene was used to observe the anti-inflammation. The analgesic effect was tested by acetic acid writhing test and hot plate test.Results:
The eth-anol extract of Folium Pyrrosiae could markedly inhibit the mouse auricle swelling induced by xylene (P<0. 01), and had the ability to inhibit the twisting induced by acetic acid in the mice (P <0. 05). The ethanol extract of Folium Pyrrosiae could increase the threshold of pain in the mice significantly after the 1-hour and 2-hour treatment (P<0. 05). The water extract of Folium Pyrrosiae could inhibit the mouse auricle swelling induced by xylene and the writhing reaction induced by acetic acid (P<0. 05). The water ex-tract of Folium Pyrrosiae could increase the threshold of pain in the mice significantly after the 1-hour treatment (P<0. 05). Conclu-sionFolium Pyrrosiae has obvious analgesic and anti-inflammatory effects.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
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