Analysis of etiology and clinical characteristics of neonatal hyperbilirubinemia / 中国基层医药

ABSTRACT

Objective To investigate the clinical characteristics and risk factors of neonatal hyperbilirubinemia.Methods The clinical data of 826 cases with neonatal hyperbilirubinemia were retrospectively analyzed.The jaundice appeared time,clinical characteristics were monitored,and the causes of jaundice appeared were analyzed.Results The jaundice cases at ≤ 1 day,＞ 1 ～ 7 days,more than ＞ 7 days were 71 cases,471 cases,284 cases,accounted for 8.60％,57.02％,34.38％ ;The top three risk factors of jaundice constitute were breast milk jaundice,perinatal factors,infectious factors,the cases were 215 cases,206 cases,200 cases,the proportions were 26.03 ％,24.94％,24.21％ ;The proportion jaundice of newborn caused by ABO hemolytic was 9.44％ ;There were 220 cases of 812 cases had neonatal jaundice,including 170 cases of full-term of breast milk jaundice,the proportion was 27.15％,50 cases of preterm infants of breast milk jaundice,accounted for 26.88％,there was no significant difference(P ＞ 0.05) ;78 cases was full-term breast milk jaundice,the proportion was 22.94％,120 cases of cesarean section appeared breast milk jaundice,accounting for 36.81％,the difference was statistically significant(P ＜ 0.05).Conclusion The degree of neonatal jaundice is affected by many factors,which related with individual differences,geographical,economic and cultural level,race,gender,feeding methods,genetic and so on,the strict observation and identification of neonatal jaundice and the establishment of supervision system and the protection for active and effective measures,taking active and effective treatment have very good effect to reduce hyperbilirubinemia complication as well as a good effect on the prevention and treatment of neonatal hyperbilirubinemia.