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Application of ThinPrep cytology test in the diagnosis of lung cancer / 中国医师进修杂志
Article in Zh | WPRIM | ID: wpr-475906
Responsible library: WPRO
ABSTRACT
Objective To explore the diagnostic value of bronchofiberscopic washing cytology (BWC) and bronchoalveolar lavage fluid (BALF) ThinPrep cytology test (TCT) in the diagnosis of lung cancer.Methods Three hundred and eighty-five lung cancer patients who completed the BWC and BALF TCT were selected.The sensitivity was compared between the conventional smear and the two TCT methods.The sensitivity and accuracy of BWC and BALF TCT in the diagnosis of lung cancer were analyzed.Results The sensitivity of TCT was 76.1% (293/385) in the diagnosis of lung cancer,and conventional smear was 54.8% (211/385).The sensitivity of TCT was significantly higher than that of conventional smear (P < 0.05).In the diagnosis of central lung cancer,the sensitivity of BWC TCT and BALF TCT was 74.4% (131/176) and 70.5% (124/176),and there was no statistical difference (P > 0.05).In the diagnosis of peripheral lung cancer,the sensitivity of BALF TCT and BWC TCT was 83.3% (174/209) and 44.0% (92/209),and there was statistical difference (P < 0.05).In BWC TCT,the accuracy of TCT and histology in squamous cancer was 92.7% (127/137),in adenocarcinoma was 92.6% (151/163),in small cell cancer was 96.8% (61/63),and total accuracy was 91.9% (354/385).In BALF TCT,the accuracy of TCT and histology in squamous cancer was 92.0% (126/137),in adenocarcinoma was 94.5% (154/163),and in small cancer was 98.4% (62/63),and total accuracy was 92.7% (357/385).Conclusions TCT has more diagnostic value in lung cancer.BWC and BALF TCT show different sensitivity in the diagnosis of lung cancer of different kinds.BWC TCT combination with BALF TCT is helpful to improve the diagnosis of lung cancer.
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Full text: 1 Index: WPRIM Type of study: Diagnostic_studies Language: Zh Journal: Chinese Journal of Postgraduates of Medicine Year: 2014 Type: Article
Full text: 1 Index: WPRIM Type of study: Diagnostic_studies Language: Zh Journal: Chinese Journal of Postgraduates of Medicine Year: 2014 Type: Article