Rapid monitoring and prevention of methicillin-resistant Staphylococcus aureus in ICU / 国际检验医学杂志

ABSTRACT

Objective To understand the colonization ,distribution and prevention of methicillin‐resistant Staphylococcus aureus (MRSA) in ICU .Methods The nasal vestibule swabs were immediately taken from new patients in ICU and the sputum suction catheter specimens were collected from the patients conforming to respiratory tract infection at 72 h after entering ICU .The fluores‐cence PCR was adopted to rapidly detect mecA ,nuc gene .The related environment specimens such as nasal cavity and hands in med‐ical staffs were performed the regular tracking monitoring ,prevention and control .Results The MRSA‐detection rates were 9 .9%for nasal vestibule swabs ,2 .7% for sputum suction catheter ;7 .1% for nasal vestibule swabs of medical staffs ,4 .0% for hands and 4 .4% for cuffs;the medical staffs and patient′s nasal cavity with MRSA‐positive adopted mupirocin for scrubing ,MRSA detection rate in hands after reinforce disinfection was 0 .0% ,but nasal cavity MRSA in medical staff was still detected out every quarter . Conclusion The PCR method has significantly higher positive detection rate compared with the conventional culture method .Nasal vestibule is a major colonization site of M RSA and the main infection source of infection ,the hands are the important route of trans‐mission ,monitoring nasal vestibule in ICU patients and medical staffs and hands in medical staffs is important to control MRSA nosocomial infection .