Pathological Findings of Crohn's Disease in the Stomach
Korean Journal of Pathology
;
: 269-273, 2006.
Article
in Korean
| WPRIM
| ID: wpr-47608
ABSTRACT
BACKGROUND:
The incidence of Crohn's disease in the upper digestive tract, and especially in the stomach, is recently increasing. Focal inflammatory reaction without Helicobacter pylori (H. pylori) infection is thought to be the characteristic pathologic findings suggesting Crohn's disease in the stomach. Yet gastric involvement of Crohn's disease has not been studied in Korea. We studied the endoscopic and pathologic findings of patients with Crohn's disease in the stomach by taking biopsies.METHODS:
Thirty patients with Crohn's disease who underwent gastroduodenoscopy followed by biopsies were included in the study. The pathology of the gastric biopsy specimens and the presence of H. pylori were evaluated.RESULTS:
Among 30 cases, 22 cases (73.3%) were H. pylori negative and 8 cases (26.7%) were H. pylori positive. For the H. pylori negative cases, all but one cases showed pit abscess and focal lymphocytic collections in the antrum. Granulomas were found in 6 cases (20%) and they were exclusively located in the antrum.CONCLUSIONS:
In the stomach, pit abscess and focal lymphocytic collections that are not associated with H. pylori infection are the characteristic pathologic findings found in Crohn's disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Stomach
/
Biopsy
/
Crohn Disease
/
Incidence
/
Helicobacter pylori
/
Gastrointestinal Tract
/
Abscess
/
Granuloma
/
Korea
Type of study:
Diagnostic study
/
Incidence study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Pathology
Year:
2006
Type:
Article
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