Progress in Stat3 and SirT1 gene in the pathogenesis of rheumatoid arthristis / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1001-1003, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-476609
ABSTRACT
Rheumatoid arthritis ( RA) is a chronic inflammatory disease involving progressive articular damage cause by inflam-matory cells and synoviocytes.Stat3 gene, which is confirmed to play a role in the pathogenesis of RA, regulates the metabolism and apoptosis of the fibroblast-like synoviocytes ( FLS) .SirT1 gene relating to the bone formation was indicated to play a role in the patho-genesis of RA in recent years.This review introduces the pathogenesis and targeted treatment of RA and makes a prediction about the relation between Stat3 and SirT1 gene.We hope it will provide a new direction for the research of RA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2015
Type:
Article
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