The research about the clinical infection distribution and drug resistance change of Staphylococcus aureus in Sanya / 国际检验医学杂志

ABSTRACT

Objective To retrospective analysis the distribution of Staphylococcus aureus infection ,and to study their drug re‐sistance change ,then to provide the basis for clinical anti‐infection treatment .Methods The clinical infection distribution and drug susceptibility test results was tested in 406 strains of Staphylococcus aureus which were isolated from the specimens of 13175 cases from January 2012 to December 2012 ,then analysis these results using statistical methods ;Isolated strains were identified by VITEK 2 Compact type automatic microbial identification and drug susceptibility system ,accompanied with drug sensitive test using Staphylococcus aureus identification and drug susceptibility analysis system test plate of Zhuhai Meihua Medical Technology com‐pany .Results The highest separation rates of Staphylococcus aureus in all clinical departments infection distribution were in de‐partment of pediatrics and neurosurgery .The highest separation rates of all kinds of clinical specimen were sputum and pus .For Staphylococcus aureus ,the lowest resistant rates were in daptomycin and vancomycin ,whose rates were both zero ;the drug resist‐ance of MRSA strains was obviously higher than that of the drug resistance of non‐MRSA strains .The reduced susceptibility to vancomycin in Staphylococcus aureus in screening showed that the drug resistance rate was rising .Conclusion Staphylococcus au‐reus in Sanya kept a good sensitivity of daptomycin and vancomycin ,these two drugs can still be the first choice drug for clinical an‐ti‐infection treatment .