Analysis on the allergens specific IgE in patients with allergic diseases / 国际检验医学杂志

ABSTRACT

Objective To explore the positive distribution characteristics of common allergen specific immunoglobulin E(slgE)in patients with suspected allergy in the Affiliated Zhongshan Hospital of Sun Yat-sen University.Methods Fluorescence enzyme linked immunosorbent assay was used to detect the serum sIgE antibody of 1 884 patients with suspected allergy diseases,including four kinds of inhalant allergens combinations (dust mites,mold,animal skin,pollen)and four kinds of food allergens combinations (seafood,cereals,meat,dairy products)from March to October 2014.The slgE expression situation of different allergen,different gender and age in allergic patients were compared.Results The slgE positive rates of dust mites,animal fur,mildew,pollen in in-haled allergens were 73.9%,8.5%,6.5%,4.0%.The positive rates of seafood,dairy products,cereals,meat in food allergens were 47.8%,31.5%,23.0%,8.5%.The slgE positive rate of patients with allergic diseases who were allergic to two kinds or more mixed allergens was up to 82.0%,and often allergic to dust mites and animal fur.The slgE positive rate of different gender had no significant difference (P >0.05).The slgE positive rate decreased as age increased.Conclusion Dust mites are the main inhalant al-lergens combination,seafood,dairy products and cereals are the main food allergens combinations.Patients with allergic disease are allergic mixed allergens.SlgE positive rate decreases with increasing age.