Preliminary study of transrectal ultrasound-guided lauromacrogol injection for treating benign prostate ;hyperplasia in elderly patients / 中华超声影像学杂志

ABSTRACT

Objective To observe the preliminary curative effect of transrectal ultrasound-guided lauromacrogol injection for treating benign prostate hyperplasia in elderly patients.Methods Forty-two patients with benign prostate hyperplasia combined with lower urinary tract symptonms received transrectal ultrasound-guided lauromacrogol injection.Then they were followed up after 3,6,12 months respectively. Prostate volume changes before and after treatment,international prostate symptom score(IPSS),postvoid residual volume (PRV ),maximum urinary flow rate (Qmax ) and features of contrast-enhanced ultrasonography before and after treatment were observed.Complications were analyzed.Results Before treatment,prostate volume,IPSS,PVR of patients were (57.3±1 7.7)ml,(28.3 ±5.2)points,(143.8±82.5) ml respectively,12 months after treatment,they reduced to (44.8 ±6.1 )ml,(8.8 ± 1 .4)points,(28.9 ±9.5 ) ml,there were statistical diffrences between before and after treatment(P <0.05 ).Qmax increased from (5.9±3.2)ml/s to (14.9 ±3.1 )ml/s (P <0.05).Contrast-enhanced ultrasonography showed filling defect sign in prostatic inner gland.No serve complications occurred.Conclusions Transrectal ultrasound-guided lauromacrogol injection for treating benign prostate hyperplasia has the characteristics of minimally invasive,safe,effective and economical.It applies to elderly patients who are unable or unwilling to have surgery.