Analysis of the thyroid hormone changes in pregnant women of different gestational age / 中国基层医药

ABSTRACT

Objective To explore thyroid related hormones levels and clinical significance of the different gestational age pregnant women.Methods 80 pregnant women for prenatal examination in our hospital were selected,including early pregnancy group 26 cases,mid -term group 33 cases and late pregnancy group 21 cases. They were taken venous blood centrifugal separation of serum,automatic biochemical analyzer was used to detect thyroid stimulating hormone (TSH),free triiodothyronine three (FT3 ),free thyroxine (FT4 )levels and associated hormone levels during pregnancy were compared.Results TSH level of early pregnancy group (1.28 ±0.23)mIU /L and mid -term group (1.56 ±0.28)mIU /L were significantly lower than non -pregnant (1.95 ±0.35)mIU /L(t =8.12,7.61,all P 0.05).A -TG positive rate (4.76%)and TPOAb positive rate (4.76%)of late pregnancy group was significantly lower than the early pregnancy group and mid -term group (χ2 =9.10,9.65,8.89,7.56,all P <0.05).Conclusion The levels of thyroid related hormone in different gestational age and autoantibody positive rate had significant differences, clinical pregnancy checks should be strengthened and control in the normal range,in order to achieve the purpose of prenatal and postnatal care.