DNA methylation of glioma related gene and its significance / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 762-765, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-479624
ABSTRACT
DNA methylation is closely related to the genesis and development of glioma.The CpG islands hypermethylation in promoter region of DNA repair genes,cell cycle controlling genes,apoptosis related genes,tumor suppressor genes and invasion related genes are found in glioma.Finding the specific methylation profile and molecular marker of glioma is helpful for the pathology class,early diagnosis and prognostic evalua-tion.Meanwhile,DNA methylation has the characteristic of reversibility,which may provide new ways for the treatment of glioma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Screening study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2015
Type:
Article
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