Abnormal Autophagy in Pathogenesis of Inflammatory Bowel Disease / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 683-686, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-479836
ABSTRACT
Inflammatory bowel disease( IBD)is a chronic and nonspecific intestinal inflammatory disease caused by multiple factors such as environment,genetic susceptibility and immune disturbance. Autophagy plays an important role in cellular homeostasis and immune. Autophagy abnormalities may be involved in the pathogenesis of IBD. Genome-wide association studies(GWAS)have provided compelling evidence that autophagy related genes,including ATG16L1,IRGM and NOD2,are significantly associated with IBD. This article reviewed the abnormal autophagy in pathogenesis of IBD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2015
Type:
Article
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