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Temporal alteration of stone composition and onset age in the upper urinary tract: a cross-sectional study of 1 878 cases / 中华泌尿外科杂志
Chinese Journal of Urology ; (12): 620-623, 2015.
Article in Chinese | WPRIM | ID: wpr-479857
ABSTRACT
Objective To investigate if distribution of stone composition and onset age in the upper urinary tract changed during the past 12 years in China.Methods There were 1 878 urolithiasis patients of the upper urinary tract in our hospital from 2003 to 2014 enrolled in present cross-sectional study.There were 1 300 male and 578 female patients with a median onset age of 46 (6-95) years.Stone composition was measured by infrared spectrophotometry.All the patients were divided into 3 groups according to the onset yearYear 2003-2006,Year 2007-2010 and Year 2011-2014.The distributions of stone types were compared among the 3 groups.Age and gender were included as potential confounders.Chi square test,P trend test,Kruskal-Wallis test and logistic regression were employed in the statistical analysis.Results Calcium oxalate was the most common type with a dominant proportion of 78.1% (1 466/1 878),while uric acid had a small proportion of 4.8% (91/1 878).The proportions of uric acid in the 3 groups were 2.7% (12/441),5.1% (39/758) and 5.9% (40/679),showing an increasing trend (P <0.05).Multivariate analysis showed that year group was independently correlated with the proportion of uric acid,with an OR of 1.385 (95% CI,1.027-1.867).From 2003 to 2014,the proportion of uric acid calculus increased by 0.42% (95% CI,0.25%-0.59%) annually.The median ages of disease onset were 43,46 and 49 years respectively in those three groups,also showing an increasing trend with time (P <0.01).Conclusion From 2003 to 2014,the proportion of uric acid and onset age in patients of upper urinary tract calculi were increased in the present cohort.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study / Prevalence study Language: Chinese Journal: Chinese Journal of Urology Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study / Prevalence study Language: Chinese Journal: Chinese Journal of Urology Year: 2015 Type: Article