Research status of relationship between breast neoplasm and type 2 diabetes mellitus / 肿瘤研究与临床

ABSTRACT

Breast neoplasm is the most common malignancy of women,along with the increasing aging population,patients with breast cancer and diabetes gradually increased,the study found some associations between breast cancer and diabetes.Type 2 diabetes mellitus can promote the occurrence of breast cancer,and type 2 diabetes mellitus can also increase the incidence of breast cancer.Its associated mechanisms include hyperglycaemia,hyperinsulinemia and insulin resistance,insulin-like growth factor-1,vascular endothelial growth factor,etc.