Your browser doesn't support javascript.
loading
Comparison of various sedative regimens during TACE for hepatocellular carcinoma / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery ; (12): 454-457, 2015.
Article in Chinese | WPRIM | ID: wpr-481028
ABSTRACT
Objective To investigate the efficacy and safety of using various sedative regimens during transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).Methods 156 HCC patients were randomly divided into four groups.The control group (n =30)intramuscular injection of 10 ml saline;The diazepam group (n =42)intramuscular injection of 10 mg of diazepam;The promethazine group (n =42)intramuscular injection of promethazine 25 mg;and The combined group (n =42)intramuscular injection of 10 mg of diazepam and promethazine 25 mg.Results The blood pressure and heart rate of the control group was significantly higher than the other three groups,while the combined group was significantly lower than the diazepam and the promethazine groups.The sedative ratingGrade 0 of the four groups were30,11,18,0 patients respectively;Grade 1 of the four groups were0,21,15,24 patients respectively;Grade 2 of the four groups were0,10,9,18 patients respectively;No patients were in grades 3 and 4.The anxiety score of the control group was significantly higher than the other three groups.There was no significant difference in complications among the four groups.Conclusion Diazepam and/or promethazine could be used effectively and safely during TACE,and they could reduce stress response of HCC patients during TACE,and improved tolerance of TACE.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Hepatobiliary Surgery Year: 2015 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Hepatobiliary Surgery Year: 2015 Type: Article