Neuroprotective activities of isorhynchophylline on Alzheimer′s disease and other central nervous systems / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1112-1115, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-481276
ABSTRACT
Isorhynchophylline ( IRN) is an alkaloid isolated from Uncaria rhynchophylla .IRN mainly acts on cardiovascular and central nervous systems diseases including hypertension , brachycardia and sedation .In recent years , it has been found that IRN has widespread pharmacological effects in central nervous disease .This review aim at reviewing neuroprotective activities of Isorhynchophyl-line on Alzheimer′s disease and other central nervous systems diseases via improving learning and memory impairments , inhibiting Tau protein hyperphosphorylation , antagonizing β-Amyloid-iInduced neurotoxicity , and reducing glia-secretory inflammatory factors .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2015
Type:
Article
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