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Neuroprotective activities of isorhynchophylline on Alzheimer′s disease and other central nervous systems / 医学研究生学报
Journal of Medical Postgraduates ; (12): 1112-1115, 2015.
Article in Chinese | WPRIM | ID: wpr-481276
ABSTRACT
Isorhynchophylline ( IRN) is an alkaloid isolated from Uncaria rhynchophylla .IRN mainly acts on cardiovascular and central nervous systems diseases including hypertension , brachycardia and sedation .In recent years , it has been found that IRN has widespread pharmacological effects in central nervous disease .This review aim at reviewing neuroprotective activities of Isorhynchophyl-line on Alzheimer′s disease and other central nervous systems diseases via improving learning and memory impairments , inhibiting Tau protein hyperphosphorylation , antagonizing β-Amyloid-iInduced neurotoxicity , and reducing glia-secretory inflammatory factors .

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Medical Postgraduates Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Medical Postgraduates Year: 2015 Type: Article