Study of survival time and treatment effect after highly active antiretroviral therapy for HIV/AIDS patients in Guangxi / 实用医学杂志

ABSTRACT

Objective To study the treatment of highly active antiretroviral therapy (HAART) in patients with HIV infection and AIDS and the patients′ survival time after HAART treatment. Methods Three thousand and one hundred cases of HIV infection and AIDS patients received HAART in 12 months by monthly flow cytometry instrument MultiSET absolute counting method detecting the CD4+T cell levels, bDNA method (detection range 1.60 log ~ 6.10 log RNA copies/mL) detecting serum HIV-1 viral load under rigorous clinical observation. Results Twelve months after treatment, the CD4+T cell count increased an average of 430 × 106/L (P < 0.01). Eight months after treatment, all viral loads reached their measurable levels (below 1.70 log copies/mL) by decreasing 45 log copies/mL on average. Conclusion HIV/AIDS patients showed treatment extremely significant possitive responses to highly active antiretroviral therapy. The patients′ survival rate after treatment has greatly improved compare to that in previous literature.