Research progress on the function of kinesin-2 family proteins in model organisms / 中国实验动物学报
Acta Laboratorium Animalis Scientia Sinica
;
(6): 517-522, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-482143
ABSTRACT
Kinesin-2 family proteins, including KIF3A, KIF3B, KIF3C and KIF17, are members of the kinesin superfamily motor proteins , which transport various proteins and vesicles in the cell and play diverse biological functions . Recently, studies on members of kinesin-2 family proteins suggest that they play fundamental roles during ciliary transport , whose defects can lead to abnormal cilia development , the major cause of human ciliopathies .In this review , we will sum-marize the functions of this motor protein family during ciliogenesis and focus mainly on their roles in the development of model organisms .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Laboratorium Animalis Scientia Sinica
Year:
2015
Type:
Article
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