Analysis of clinical effect of periodontic treatment in type 2 diabetic patients with chronic periodontitis / 中国糖尿病杂志

ABSTRACT

Objective To explore the clinical effect of periodontic treatment in type 2 diabetic patients (T2DM ) with chronic periodontitis on basis of hypoglycemic therapy. Methods From September 2011 to January 2014 ,120 T2DM patients with chronic periodontitis were selected and divided into treatment group and control group with 60 cases in each group. Patients in control group were treated with conventional hypoglycemic therapy. Patients in treatment group were treated with initial periodontal therapy additionally on basis of conventional hypoglycemic therapy. Probing depth (PD) ,attachment loss (AL) ,plaque index (PLI) ,bleeding index (BI) and hypersensitive C reactive protein (hsC‐RP) levels were compared before and after 6 weeks treatment. Results PD ,AL ,PLI ,BI ,and hsC‐RP levels had no significant difference between two groups before treatment (P>0.05). PD ,AL ,PLI ,BI and hsC‐RP levels after treatment in treatment group were all significantly decreased [PD(2.11 ± 0.28) vs (2.51 ± 0.68) and (2.42 ± 0.31) mm ;AL(3.18 ± 0.41) vs (3.58 ± 0.83) and (3.49 ± 0.58) mm ;PLI(0.41 ± 0.21) vs (0.96 ± 0.33) and (0.78 ± 0.26);BI(0.97 ± 0.32) vs (2.65 ± 1.21) and (1.14 ± 0.30);hsC‐RP(1.02 ± 0.63) vs (3.29 ± 2.88) and (2.72 ± 1.51) mg/L] as compared with those before treatment in treatment group and those after treatment in control group (P<0.05). Conclusion Levels of inflammatory factors will decrease when periodontic treatment is added to the antidiabetic therapy in T 2DM patients with chronic periodontitis.