Your browser doesn't support javascript.
loading
The TGF-β signaling pathway induced EMT in breast cancer / 药学学报
Acta Pharmaceutica Sinica ; (12): 385-92, 2015.
Article in Zh | WPRIM | ID: wpr-483334
Responsible library: WPRO
ABSTRACT
Epithelial-mesenchymal transition (EMT) refers to tne transition during which epithelial cells undergo the loss of apical-basal polarity, acquisition of migration capability and transformation into mesenchymal cells. EMT induces breast cancer in situ to developing into metastasis and associates with the drug resistence. The multiple elements including signal pathways, transcriptional factors and downstream genes orchestrate the transition. Among them, the transforming growth factor β (TGF-β) signaling pathway plays a key role in the regulation of EMT in breast cancer. And this paper reviews the development of TGF-β signaling pathway induced EMT in breast cancer.
Full text: 1 Index: WPRIM Language: Zh Journal: Acta Pharmaceutica Sinica Year: 2015 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Acta Pharmaceutica Sinica Year: 2015 Type: Article