Study on the HPLC Fingerprint of Glycyrrhizae Dispensing Granules / 中国药师
China Pharmacist
;
(12): 2053-2057, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-484687
ABSTRACT
Objective:
To establish an HPLC method for the fingerprint determination of glycyrrhizae dispensing granules. Meth-odsTwelve samples were analyzed by HPLC with glycyrrhizic acid as the reference. The analysis was performed on a Waters SunFire C18 column(250 mm × 4. 6 mm,5 μm) with the mobile phase A of acetonitrile and the mobile phase B of 0. 1% phosphoric acid solu-tion with gradient elution. The flow rate was 1. 0 ml·min-1 , the detection wavelength was 237nm, and the column temperature was 30℃.Results:
By analyzing the fingerprint, 21 peaks existed including the peak of liquiritin and glycyrrhizic acid. The similarity of the samples was more than 0. 97.Conclusion:
The established HPLC fingerprint of glycyrrhizae dispensing granules is dependable and simple. The method can provide scientific basis for the quality control of glycyrrhizae dispensing granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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