Influence of icaritin in proliferation and apoptosis of NB4 leukemia cells and its mechanism / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
;
(6): 1181-1185, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-485569
ABSTRACT
of NB4 cells at S phase was lower than those in control group (P <0.05),and the number of NB4 cells at G1 phase was increased (P <0.05).The expression levels of Bcl-2 in ICA groups were significantly lower than that in control group (P < 0.05 ), while the expression levels of Bax were higher than that in control group (P < 0.05 ). Conclusion ICA can induce the apoptosis of NB4 cells via inhibiting the expression level of Bcl-2 and up-regulating the expression level of Bax.
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Jilin University(Medicine Edition)
Year:
2015
Type:
Article
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