Rapid-Onset Hyponatremia Induced by Duloxetine in a Middle-Aged Male with Depression and Somatic Symptoms
Psychiatry Investigation
;
: 83-84, 2012.
Article
in English
| WPRIM
| ID: wpr-48597
ABSTRACT
Duloxetine is a relatively balanced selective serotonin and noradrenaline reuptake inhibitor. We report a case of hyponatremia induced by duloxetine developed rapidly after starting the medication in a middle-aged male with multiple somatic symptoms and depression. Two days after discontinuation of duloxetine and management with hypertonic saline as well as fluid restriction, the serum sodium level normalized. The patient had two risk factors for developing hyponatremia, such as severe body weight loss and pneumonia. Therefore, when treating patients with depression and somatic symptoms, especially with risk factors for developing hyponatremia, close monitoring for clinical and laboratory evidence of hyponatremia may be essential.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Sodium
/
Thiophenes
/
Body Weight
/
Serotonin
/
Norepinephrine
/
Risk Factors
/
Depression
/
Duloxetine Hydrochloride
/
Hyponatremia
Type of study:
Diagnostic study
/
Etiology study
/
Risk factors
Limits:
Humans
/
Male
Language:
English
Journal:
Psychiatry Investigation
Year:
2012
Type:
Article
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