The histological observation of the inhibitory effects of baicalin in lipopolysaccharide-induced periodontitis in rats / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 133-134, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-486016
ABSTRACT
50 adult male SD rats were divided randomly into 5 groupsA,B,C1 ,C2,C3(n =1 0).The rats in roup A was used as a blank controls.The rats in group B and C were with LPS induced periodontitis,those in group C1 ,C2 and C3 received 0.2 ml of baicalin daily injection(0.01 ,0.1 and 1 .0 μg/ml respectively)into the gingival sulcus of the teeth with periodontitis for 3 days.The rats were sacri-ficed 7 days after treatment and periodontal tissues of the related teeth were observed by histology.In group C1 ,C2 and C3 the periodontal inflammation was significantly slighter than that in group B,the osteoclasts count was as followingB >C1 >C2 >C3 >A(P <0.05).The study suggests that baicalin can inhibit destructive effect of LPS to periodontal tissue of rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS