Clinical Efficacy of Salvia Miltiorrhiza Ligustrazine Combined with Alprostadil Injection in the Treatment of Diabetic Nephropathy / 中国药师

ABSTRACT

Objective:To observe the curative effect and safety of salvia miltiorrhiza ligustrazine combined with alprostadil injec-tion in the treatment of diabetic nephropathy. Methods: Totally 84 patients with diabetic nephropathy admitted in our hospital from January 2012 to December 2013 were randomly divided into the observation group and the control group with 42 cases in each. Alpros-tadil injection was applied in the control group, and salvia miltiorrhiza ligustrazine combined with alprostadil injection was used in the observation group. The clinical efficacy of the two groups was compared. Results:The total effective rate was 95. 2% in the observa-tion group, which was significantly higher than that (83. 3%) in the control group (P<0. 05). BUN, Scr and urine former protein levels after the treatment were significantly lower than those before the treatment (P<0. 05), and the renal function in the observation group was significantly better than that in the control group (P<0. 05). Conclusion:Salvia miltiorrhiza ligustrazine combined with al-prostadil injection in the treatment of kidney disease is effective to promote the discovery of renal function, which is worthy of promoted application in clinical practice.