Optimization of Chitosan Flocculation Purification Process of Zhigancao Decoction by Orthogonal Test / 中国药师
China Pharmacist
;
(12): 477-479, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-487710
ABSTRACT
Objective:
To optimize the chitosan flocculation purification process of Zhigancao decoction.Methods:
With the total content of ginsenoside Rg1 , Re and Rb1 and the impurity removal rate as the evaluation indices, an orthogonal test was used to investi-gate the effects of concentration of solution, amount of chitosan and standing temperature on the purification process.Results:
The op-timum conditions of chitosan flocculation clarification process of Zhigancao decoction were as followsthe concentration of extraction so-lution was 0. 25 g·ml-1 , the standing temperature was 25℃, and the amount of chitosan was 12% .Conclusion:
The optimum con-ditions of purification process are promising with high impurity removal rate and active ingredients retention rate, which provide refer-ence for the dosage form reformation of Zhigancao decoction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2016
Type:
Article
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