Clinical Effects of Gamma Globulin at Different Doses Combined with Dexamethasone in the Treatment of Children with Severe Idiopathic Thrombocytopenic Purpura / 中国药师
China Pharmacist
;
(12): 538-540, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-487727
ABSTRACT
Objective:
To explore the efficacy of gamma globulin at different doses combined with dexamethasone in the treatment of children with severe idiopathic thrombocytopenic purpura.Methods:
Totally 96 cases of patients with idiopathic thrombocytopenic purpura were divided into group A ( standard high dose of gamma globulin+dexamethasone) , group B ( middle dose of gamma globulin+dexamethasone) and the control group ( dexamethasone) . The clinical effects and platelet parameters of the three groups were com-pared.Results:
The levels of PLT, PCT and PDW in group A and group B after the treatment were higher than those in the control group(P0. 05). The clinical effective rate of group A and group B was higher than that in the control group(P0.05). There was no significant difference in the incidence of adverse reactions among the three groups (P>0. 05).Conclusion:
Gamma globulin at middle dose shows significant effect as at high dose in the patients with ITP, which can reduce the dosage and is worthy of clinical promotion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2016
Type:
Article
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