Study on acute urticaria syndrome due to drug allergy of in-patient at the Department of Allergology and Clinical Immunology of Bach Mai Hospital (2001-2005)

ABSTRACT

The cross sectional study was conducted in 111 patients suffered from acute urticaria due to drug allergy at the Department of Allergology and Clinical Immunology of Bach Mai Hospital from January 2001 to May 2005. Results: these patients were allergic to 120 kinds of medications; antibiotic were the leading cause of the acute urticaria with 55.8%, among which beta lactam is the most common cause; then traditional medications with 15.8% … Patients often included 2 groups <20 and 20-39 years (34.2%), women more than men (p<0.005). The rate of oral allergy accounted for 88.3%; 50.4% of patients had allergic history. Allergy to one kind of medication 91.9%. The duration of acute urticaria was from 1 to 24 hours (48.6%). Increase of erythrocyte sedimentation rate occurred in 62.2% of patients. The duration of treatment was 6.57±3.56 days. The patients were treated with glucocorticoid and antihistamine, mainly methyl-prednisolon and dimedrol. 100% of patients recovered