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Urinary continence and pathological outcome after bladder neck preservation during radical prostatectomy: a systematic review and meta-analysis / 中华泌尿外科杂志
Chinese Journal of Urology ; (12): 174-178, 2016.
Article in Chinese | WPRIM | ID: wpr-488693
ABSTRACT
Objective To conduct a systematic review to evaluate efficacy and safety of bladder neck preservation techniques during radical prostatectomy.Methods We searched PubMed,Embase,Medline,Central (the Cochrane Library,Issue 1,2013),CNKI,CBM from the inception to July 2015 for randomized or observational studies assessing the influence of preservation of bladder neck on the continence recovery and cancer control outcomes after radical prostatectomy.Two researchers evaluated the quality of included studies.A meta-analysis was conducted using Review Manager 5.0 software.Results Twelve observational and two randomized studies were analyzed.BNP group had a faster recovery of early continence than non-BNP group at 1 month[OR =2.88,95% CI 1.80-4.60,P < 0.05],3-4 months [OR =2.32,95% CI 1.42-3.80,P < 0.05].However there was no statistically significant difference in terms of continence rate at 6 months [OR =1.49,95% CI 0.97-2.29,P =0.07] and 12 months [OR =0.99,95% CI 0.70-1.39,P =0.93] among two groups.There was no significant difference in terms of PSM rate [OR =0.92,95 % CI 0.71-1.19,P =0.52] between BNP and non-BNP groups.Conclusions We found that preservation of the bladder neck result in earlier return of urinary continence without adversely affecting cancer control.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial / Observational study / Systematic reviews Language: Chinese Journal: Chinese Journal of Urology Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial / Observational study / Systematic reviews Language: Chinese Journal: Chinese Journal of Urology Year: 2016 Type: Article