Research progress in the field of stem cells in bone regeneration / 国际生物医学工程杂志

ABSTRACT

Stem cells are the origin cells of human body with high proliferation ability, multi-directional differentiation potential and self-renewal ability, which can be divided into embryonic stem cells and adult stem cells.In recent years, great progress has been made in the research and developnent of bone tissue engineering, and applied in more and more hospitals.Research on stem cells brings new hope to oral tissue engineering and has an important significance for bone regeneration.To obtain the seed cells with strong proliferation ability and osteogenic potential is critical for bone tissue engineering construction.Odontogenic stem cells, bone marrow mesenchymal stem cells, adipose tissue-derived stem cells and embryonic stem cells have become important sources of bone tissue regeneration therapy due to their excellent regeneration and differentiation potential.This review aims to summarize the bone regeneration ability of stem cells which draws more attentions at present, and discuss the application prospect.