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Pediatric inherited cancer predisposition syndromes and TP53 germ-line mutation / 临床儿科杂志
Journal of Clinical Pediatrics ; (12): 333-337, 2016.
Article in Zh | WPRIM | ID: wpr-489894
Responsible library: WPRO
ABSTRACT
Pediatric inherited cancer predisposition syndromes are a group of diseases caused by germ-line mutation of cancer related genes. The patients are susceptible to cancers. TP53 germ-line mutation is the most commonly seen mutant gene in cancers that accounts for 20%-30%of all germ-line mutations of inherited cancers. TP53 gene mutation screening could help clinicians to better manage the patients and their family members.
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: Journal of Clinical Pediatrics Year: 2016 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Journal of Clinical Pediatrics Year: 2016 Type: Article