Pediatric inherited cancer predisposition syndromes and TP53 germ-line mutation / 临床儿科杂志
Journal of Clinical Pediatrics
; (12): 333-337, 2016.
Article
in Zh
| WPRIM
| ID: wpr-489894
Responsible library:
WPRO
ABSTRACT
Pediatric inherited cancer predisposition syndromes are a group of diseases caused by germ-line mutation of cancer related genes. The patients are susceptible to cancers. TP53 germ-line mutation is the most commonly seen mutant gene in cancers that accounts for 20%-30%of all germ-line mutations of inherited cancers. TP53 gene mutation screening could help clinicians to better manage the patients and their family members.
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Clinical Pediatrics
Year:
2016
Type:
Article