The curative effect of Xingnaojing injection in the treatment of children febrile convulsion / 中国基层医药

ABSTRACT

Objective To explore the influence of Xingnaojing injection on the duration of fever,convulsions and rate of relapse in the treatment of children with febrile convulsion.Methods Reviewed the medical records of 157 patients with febrile convulsion.Patients were assigned to Xingnaojin treatment (n =68) and conventional therapy group according to whether Xingnaojing injection was added in the conventional treatment(n =89).Collected the duration of fever since they accepted treatment in hospital,whether occurred convulsion again and untoward effect,had a follow -up of 6 months,in order to record whether they had relapse.Results In Xingnaojing group,the duration of fever was (2.43 ±1.38)d,which was shorter than (3.75 ±2.24)d of the control group(t =4.28,P <0.05).The occurrence rate of convulsion again in Xingnaojing group was 11.76%,which was lower than 25.83% of the control group(χ2 =4.821,P <0.05).Following -up for 6 months,Xingnaojing group had better rate of relapse (7.35%) than the control group(20.22%) (χ2 =5.108,P <0.05).No untoward effect was observed.Conclusion Xingnao-jing injection can shorter the duration of fever and prevent convulsion,while without obvious untoward effect,could apply to the treatment of children febrile convulsion.