Observation of the effect of Kang′ai injection in the chemotherapy treatment of gastrointestinal cancer / 中国基层医药

ABSTRACT

Objective To explore the effect of Kang′ai injection in the chemotherapy treatment of gastroin-testinal cancer.Methods 97 patients with gastrointestinal cancer were divided into the control group(49 cases) and the observation group(48 cases) in accordance with the random number table.The control group received common chemotherapy treatment,while the observation group was plused Kang'ai injection based on the same treatment.The near time clinical efficacy and survival rate in three years between the two groups were compared.Results The near time total effective rate of the observation group was 89.58%, which was significantly higher than 71.43% of the control group(χ2 =19.278,P<0.05).The improvement rate of quality of life in the observation group was 68.75%, which was significantly higher than 30.61% of the control group(χ2 =10.876,P<0.05).The reduction rate of quality of life in the observation group was 10.42%,which was significantly lower than 34.69%of the control group (χ2 =12.674,P<0.05).About adverse reactions rate above Ⅲ°,the gastrointestinal in the observation group was 6.25%,which was significantly lower than 22.45%of the control group(χ2 =14.523,P<0.05).The blood adverse reactions rate in the observation group was 0.00%,which was significantly lower than 12.24% of the control group (χ2 =17.795,P <0.05).The survival rates of 1,2,3 years in the observation group were 91.67%,75.00%, 60.42%,respectively,which were significantly higher than 77.55%,59.18%,34.69% in the control group(χ2 =9.547,13.697,15.862,all P<0.05).Conclusion Kang′ai injection can improve the tolerance of gastrointestinal cancer to chemotherapy treatment,reduce adverse reactions rate,improve quality of life and prolong survival.