The value of strain rate ratio of ultrasonic imaging in the diagnosis of benign and malignant breast tumors / 中国基层医药

ABSTRACT

Objective To investigate the diagnostic value of strain rate ratio in the diagnosis of benign and malignant breast masses.Methods 80 patients with suspicious nodules(104 lesions) were selected as the research subjects.The ultrasonic diagnostic apparatus equipped with ultrasonic elastography was used for conventional ultrasound examination and comprehensive elastography.The tumor location,lesion number,lesion size,shape,smooth edge or boundary,internal lesions and peripheral echo characteristics,calcification and blood supply were recorded, and two dimensional ultrasound imaging and elastography images on the tumor area were measured,took the average value;start the elastic imaging mode, strain rate automatic generation of strain rate lesions and surrounding normal glandular tissue system,and the two strain ratio ( SR) .To determine the best diagnostic value of SR in judging the nature of the lesions.Finally,the result was evaluated by accuracy,sensitivity,specificity,positive predictive value and negative predictive value.Results In 104 breast lesions,58 lesions were benign and 46 malignant lesions were malignant.The pathological diagnosis as the final standard,using ultrasonic elastic strain rate ratio and area ratio to determine the nature of the lesion,the ratio of the strain rate(t=8.342) and the area ratio of benign and malignant lesions(t=7.541),the difference was statistically significant(all P<0.05).The results showed that the sensitivity, specificity,accuracy,positive predictive value and negative predictive value of two-dimensional ultrasound in diagnosis of breast cancer were 73.91%,86.20%,80.76%,80.95%,80.61%,respectively.The sensitivity,specificity, accuracy,positive predictive value and negative predictive value of SR in the diagnosis of breast cancer were 91.30%,89.65%,90.38%,87.50%,92.85%,respectively.The results showed that the sensitivity(χ2 =9.641), accuracy(χ2 =8.332) and negative predictive accuracy(χ2 =8.950) of two dimensional ultrasound and ultrasonic (χ2 =8.743)image were significantly higher than those of the two-dimensional ultrasound(all P<0.01),and the specificity was higher than that of the two-dimensional ultrasound(χ2 =2.421,P<0.05).Conclusion The strain rate ratio of ultrasonic elasticity imaging has important diagnostic value in breast benign and malignant tumors.Its accuracy is higher than conventional two-dimensional ultrasound.This method is not only cheap,safe,real-time, non radioactive,but also can be used in the diagnosis of the lesions,so it is worthy of clinical application.