STAT3 signaling in pathogenesis of pancreatitis / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12): 558-563, 2016.
Article
in Zh
| WPRIM
| ID: wpr-491660
Responsible library:
WPRO
ABSTRACT
Signal transducer and activator of transcription 3 (STAT3), an acute-phase response protein, is ac-tivated to over-express by cytokines .STAT3 also acts as a transcriptional factor to regulate the expression of cytokines .O-ver-expression of cytokines is accompanied by STAT 3 activation and over-expression in acute pancreatitis .Meanwhile , the proliferation of pancreatic stellate cells in chronic pancreatitis is mediated by STAT 3.In this review, the research progress in STAT3 function is summarized to elaborate its potential role in the pathogenesis of pancreatitis .
Full text:
1
Index:
WPRIM
Type of study:
Etiology_studies
Language:
Zh
Journal:
Chinese Journal of Pathophysiology
Year:
2016
Type:
Article