Expression and significance of HSPC238 in cervical intraepithelial neoplasia and cervical cancer / 中国免疫学杂志
Chinese Journal of Immunology
;
(12): 223-225, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-491732
ABSTRACT
Objective:
To investigate the expression of HSPC238 in cervical intraepithelial neoplasia and cervical cancer.Methods:
We collected 76 cases of cervical cancer,105 cases of CIN and 28 cases of normal cervical epithelial.Then we inves-tigated the expression of HSPC238 by using immunohistochemistry and compared the significant differences between them.Results:
There was no significant difference in the expression of HSPC238 between the cervical cancer and normal cervical epithelial ( Z=-0.242,P>0.05).However,there was significant difference between the cervical intraepithelial neoplasia and normal cervical epithelial (χ2=19.159,P<0.01) and the expression of HSPC238 was correlated with the grades of CIN.The expression of HSPC238 decreased when the grade of CIN was increasing.( rs=-0.327,P<0.01 ).Conclusion:
The low expression of HSPC238 might be correlated with the development of cervical neoplasia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
2016
Type:
Article
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