Population pharmacokinetics in children:research advances / 国际药学研究杂志

ABSTRACT

Children are a special group in clinical medical treatment. The significant individual differences require individual?ized administration of drugs. In recent years,the rapid development of population pharmacokinetics which are widely used in pharma?ceutical research is an effective method to achieve individual administration. At home and abroad a large number of population pharma?cokinetics are researched in chidren for drugs with narrow therapeutic window or in children with significant individual differences , which can provide information for the individualized dosing of drugs.