Semaphorin familily and glioma / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 299-301, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-493149
ABSTRACT
Semaphorins act as axon guidance molecules,which were either secretory or binding to the cell surface.All its family members contain a Sema structure,which is composed of about 500 amino acid residues and is essential for its biological activity.Functionally,they play different roles in tumors,such as oncogenes or tumor suppressor genes,and their abnormal expressions are related to the proliferation,migration and invasion of glioma cells.Semaphorins may be the therapeutic targets for the clinical treatment of glioma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2016
Type:
Article
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