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Role of Aquaporins in Modulating Diarrhea-predominant Irritable Bowel Syndrome / 胃肠病学
Chinese Journal of Gastroenterology ; (12): 380-382, 2016.
Article in Chinese | WPRIM | ID: wpr-493310
ABSTRACT
Aquaporins,known as a family of water channel proteins,are crucial factors involved in colonic transmembrane water transport and play important roles in maintaining the homeostasis of internal and external environment of intestinal cells and modulating enteric nerve functions. Diarrhea-predominant irritable bowel syndrome( IBS-D)is a commonly seen gastrointestinal functional disorder in clinical practice. Recently,there are more and more researches focusing on the roles of aquaporins in IBS-D,however,mechanisms of its protective or damaging effects on IBS-D are still not clear. In this review article,the progress of research on the modulatory effect of aquaporins in IBS-D was summarized.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Gastroenterology Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Gastroenterology Year: 2016 Type: Article