Risk Factors Study for Lung Cancer Patients with Chemotherapy-induced Severe Neutropenia / 中国药师
China Pharmacist
;
(12): 896-898, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-493993
ABSTRACT
Objective:
To discuss the risk factors in lung cancer patients with chemotherapy-induced severe neutropenia to provide reference for clinical drug use.Methods:
A retrospective analysis was performed for the patients with lung cancer,and the risk factors of severe neutropenia were statistically analyzed and found out.Results:
The results of single factor experiments showed that the incidence of severe neutropenia was related with radiotherapy history,cycles of chemotherapy and the use time of granulocyte colony factor. Based on a binary logistic regression analysis,the history of radiotherapy and the use of granulocyte colony factor were the significant risk factors of severe neutropenia in the lung cancer patients.Conclusion:
For the patients with radiotherapy history,it is better to choose chemotherapy drugs with lower toxicity,decrease drug dosage or preventively use granulocyte colony factor. The rational use of rhG-CSF can alleviate chemotherapy-induced severe neutropenia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Risk factors
Language:
Chinese
Journal:
China Pharmacist
Year:
2016
Type:
Article
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