Comparing different revascularization approaches on the prognosis of elderly patients aged 75 and over with diabetes and multi-vessel coronary artery disease / 中华老年医学杂志
Chinese Journal of Geriatrics
; (12): 147-150, 2016.
Article
in Zh
| WPRIM
| ID: wpr-494191
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ABSTRACT
Objective To evaluate the clinical effects of two different revascularization approaches,one via percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and the other via coronary artery bypass graft (CABG),on short-and long-term prognosis in elderly patients with diabetes and multi-vessel coronary artery disease.Methods A retrospective analysis was conducted on 254 elderly patients with diabetes and multi-vessel coronary artery disease.Based on the revascularization approach,patients were divided into the PCI group (n=93) and the CABG group (n =161).The incidence of major cardiovascular events (MACE) were observed during hospitalization and 1-year after follow-up.Results All-cause mortality and the incidence of non-fatal myocardial infarction were higher in the CABG group than in the PCI group during hospitalization [4.9% (8 cases) vs.1.1% (1 cases),5.6% (9 cases) vs.2.2% (2 cases),each P<0.05],while there was no significant difference in the incidence of MACE between the two groups1-year after follow-up (P> 0.05).The incidence of cerebrovascular events was lower in the PCI group than in the CABG group [2.2 % (2 cases) vs.6.2% (10 cases),P<0.05],while the rate of revascularization was higher in thePCI group than in the CABG group [6.5% (6 cases) vs.1.9% (3 cases),P<0.05].Cox regression analysis showed that diabetes (OR =1.65,95% CI:1.013-1.926,P =0.024) and left ventricular ejection fraction (OR =1.30,95 % CI:1.018-1.652,P =0.027) were independent risk factors for revascularization and cerebrovascular events.Conclusions MACEs during hospitalization are fewer in elderly patients with diabetes and multi-vessel coronary artery heart disease who received PCI than in those who received CABG.PCI has a similar mid-and long-term effect as CABG,bur PCI has a higher revascularization rate and lower risk of MACEs than CABG.
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Index:
WPRIM
Type of study:
Prognostic_studies
/
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Geriatrics
Year:
2016
Type:
Article