Determination of Five Heavy Metals in Fufang Danshen Tablets by Inductively Coupled Plasma Mass Spec-trometry with Microwave Digestion / 中国药师
China Pharmacist
;
(12): 1405-1407, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-495157
ABSTRACT
Objective:
To establish a quantitative determination method for Pb , As, Cu, Cd and Hg in Fufang Danshen tablets by inductively coupled plasma mass spectrometry ( ICP-MS) with microwave digestion .Methods:
The samples were digested by micro-wave and calibrated by the internal standard elements ( In, Ge and Bi ) , and with spinach as the controlled reference standard , the contents of Pb, As, Cu, Cd and Hg were analyzed.Results:
The minimum detection limit of Pb, As, Cu, Cd and Hg was 6.5,2.3, 5.9,4.7 and 0.91 ng· g-1, respectively, a good linear relationship was obtained respectively within the concentration range (r>0.998 0) with the average recovery of 102.8%,105.1%,104.5%,106.8%and 92.4%and RSD of 2.1%,2.8%,1.9%,2.2%and 3.4%(n=9), respectively.Conclusion:
The method is accurate and fast with little interference , and suitable for the determination of heavy metal elements in Fufang Danshen tablets .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2016
Type:
Article
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