Mechanism and prevention of brain injury in perioperative neonatal cardiac surgery / 国际儿科学杂志

ABSTRACT

Brain injury is the common perioperative complication in neonate with congenital heart disease,which seriously affects the prognosis of the patients.The pathogenesis of neonatal perioperative brain injury are closely related to genetics,brain development,surgical procedures,cardiopulmonary bypass,etc.Early prevention,diagnosis and treatment of brain injury were crucial for improving patient's survival and their quality of life.This article reviews the pathogenesis of perioperative neonatal cardiac surgery associated brain injury,and summarizes the current progress of prevention and treatment in brain injury.