Efficacy and Side Effect of Paracetamol and Tramadol Hydrochloride Tablet and Paracetamol and Dihydroco-deine Tartrate Tablet on Chronic Pain / 中国康复理论与实践

ABSTRACT

Objective To compare the efficacy and side effect between Paracetamol and Tramadol Hydrochloride Tablet and Paracetamol and Dihydrocodeine Tartrate Tablet on chronic pain. Methods From October, 2013 to October, 2015, 84 patients with chronic pain were divided into group A (n=42) and group B (n=42), who took two Tramadol tablets or Dihydrocodeine Tartrate tablets, three times a day orally for five days. They were assessed with Numerical Rating Scale (NRS), and the incidence of satisfaction and side effect were in-vestigated. Results The score of NRS decreased in both groups after treatment (t>9.402, P0.061). Conclusion The analgesic efficacy is similar of both drugs, but different in side effects of gastrointestine.