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DKI study of brain structural changes in patients with chronic alcohol dependence / 实用放射学杂志
Journal of Practical Radiology ; (12): 1005-1008, 2016.
Article in Zh | WPRIM | ID: wpr-496518
Responsible library: WPRO
ABSTRACT
Objective To investigate the association between brain structure abnormalities and neuropsychology impairment in CAD patients.Methods Nineteen patients with CAD and 1 7 healthy adults were examed with MRI,and T1 WI,T2 WI,FLAIR,DWI and DKI image were performed,and then comparing the acquired MRI findings between two groups.Results Significant differences were observed for MK values in splenium and body of the corpus callosum,left cerebellar hemisphere and amygdala cerebelli.MK values of CAD group were lower than those of healthy group in these regions,and differences were statistically significant(P <0.05). There were significant correlation between MK values of the left amygdala cerebelli and MoCA scores in CAD group.Conclusion DKI could detect the changes of brain tissue microstructure in CAD patients early.The correlation between MK and neuropsychologi-cal function provides an important basis for early diagnosis and treatment.
Key words
Full text: 1 Index: WPRIM Type of study: Screening_studies Language: Zh Journal: Journal of Practical Radiology Year: 2016 Type: Article
Full text: 1 Index: WPRIM Type of study: Screening_studies Language: Zh Journal: Journal of Practical Radiology Year: 2016 Type: Article