A Case of NCAM-positive Nasal Type T/NK-Cell Lymphoma
Annals of Dermatology
;
: 190-194, 1998.
Article
in English
| WPRIM
| ID: wpr-49661
ABSTRACT
We herein report a case of nasal type T/natural killer(NK)-cell lymphoma(TNKCL). This lymphoma is characterized by the expression of CD2, CD43 and NCAM(CD56) antigen, an aggressive clinical course, frequent extranodal spreading, a strong association with Epstein-Barr virus(EBV), and the absence of T-cell receptor(TCR) gene rearrangement. NCAM antigen is known to be a possible determinant of extranodal dissemination of peripheral T-cell lymphoma(PTCL). The patient is a 70-year-old male with skin lesion on his forearm. Histopathological and immunohistochemical studies were diagnostic of EBV-associated TNKCL. Untill now, he has failed to respond to anticancer therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
T-Lymphocytes
/
Gene Rearrangement
/
Herpesvirus 4, Human
/
Neural Cell Adhesion Molecules
/
Forearm
/
Lymphoma
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Annals of Dermatology
Year:
1998
Type:
Article
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